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Historically, repeat pregnancy loss associated with antiphospholipid antibodies was treated with combinations of prednisone and aspirin. The rationale for prednisone therapy is suppression of autoantibodies such as antiphospholipid and antinuclear antibodies. A study comparing live birth rates in women treated with heparin and aspirin with prednisone and aspirin showed 75% live births in both groups. However, both maternal complications and preterm delivery with premature rupture of membranes and toxemia of pregnancy were significantly higher in pregnant women treated with prednisone and aspirin compared with heparin and aspirin. Other side effects of steroid medication include fluid retention, weight gain and mood changes. Therefore, the current recommendation for “first attempt” treatment for repeat pregnancy loss associated with antiphospholipid antibodies is heparin and aspirin.

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“It is difficult to write reviews for fertility clinics since there is so much inherent bias in terms of whether or not one receives a positive outcome. My wife and I, both physicians, understand that online reviews are largely skewed in this regard and tend to focus on things like "customer service" and factors that are somewhat irrelevant to the quality of the medical care received. In our case, however, there is no choice but to give Dr. Acacio and his staff 5 stars.”

“If you want to be treated exceptionally well by helpful staff, a welcoming front office and a highly knowledgeable, caring and responsive clinical team, then look no further. Dr. Brian Acacio and his team helped us conceive and also made sure that we never felt alone in the process. It's an extremely dedicated group of people that genuinely help people fulfill their dream of parenthood.”

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