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Historically, repeat pregnancy loss associated with antiphospholipid antibodies was treated with combinations of prednisone and aspirin. The rationale for prednisone therapy is suppression of autoantibodies such as antiphospholipid and antinuclear antibodies. A study comparing live birth rates in women treated with heparin and aspirin with prednisone and aspirin showed 75% live births in both groups. However, both maternal complications and preterm delivery with premature rupture of membranes and toxemia of pregnancy were significantly higher in pregnant women treated with prednisone and aspirin compared with heparin and aspirin. Other side effects of steroid medication include fluid retention, weight gain and mood changes. Therefore, the current recommendation for “first attempt” treatment for repeat pregnancy loss associated with antiphospholipid antibodies is heparin and aspirin.

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“If you want to be treated exceptionally well by helpful staff, a welcoming front office and a highly knowledgeable, caring and responsive clinical team, then look no further. Dr. Brian Acacio and his team helped us conceive and also made sure that we never felt alone in the process. It's an extremely dedicated group of people that genuinely help people fulfill their dream of parenthood.”

Our Locations
  • Acacio Fertility Center
    in Laguna Niguel

    27882 Forbes Road, Suite 200
    Laguna Niguel, CA 92677

    Phone number: 949-249-9200
    Fax number: 949-249-9203

  • Acacio Fertility Center
    in Bakersfield

    2225 19th Street
    Bakersfield, CA 93301

    Phone number: 661-326-8066
    Fax number: 661-843-7706

  • Acacio Fertility Center
    in Mission Viejo

    26800 Crown Valley Parkway, Suite 560
    Mission Viejo, CA 92691

    Phone number: 949-249-9200
    Fax number: 949-249-9203