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“Now Introducing PRF (Plasma Rich Fibrin) 3-5 times more growth factors than PRP (Plasma Rich Platelets)-at the same cost.” “For both Ovarian Rejuvenation and Uterine Lining Improvement for Implantation”

“There has been a growing interest in innovative procedures aimed at rejuvenating various tissues and organs within the human body. One such procedure is the Platelet Rich Fibrin (PRF) for ovarian and uterine rejuvenation by utilizing platelet rich fibrin’s regenerative properties. This cutting-edge technique represents an exciting advancement in the field of reproductive medicine, offering a potential solution for women experiencing infertility, diminished ovarian function, and women with endometrial issues.

The Platelet Rich Fibrin procedure offers a way to harness the body’s natural regenerative abilities. Liquid PRF consists of autologous platelets, white blood cells, and fibrin derived from the patient’s own blood. It is prepared by slow centrifugation speeds of a blood sample to separate the upper plasma layer composed of liquid fibrinogen/thrombin from the other components. This concentrated mixture, rich in a multitude of growth factors and cytokines, without the addition of any natural or synthetic preparations is then injected directly into the ovaries or into the uterine cavity.

Ovarian rejuvenation refers to the restoration of ovarian function and the enhancement of the ovarian reserve, which is the pool of eggs available for insemination. The growth factors and cytokines present in PRF, simulates tissue repair, angiogenesis (formation of new blood vessels) and provides a structure for cellular attachment. This makes it an ideal tissue regeneration scaffold.

The PRF procedure is also a potentially effective solution to improve uterine health and fertility outcomes. The uterine cavity provides a receptive environment for embryo implantation and successful pregnancy. Certain conditions such as endometrial thinning, scarring, or insufficient vascularization can adversely affect the uterine lining leading to infertility or recurrent pregnancy loss. When PRF is introduced into the uterine cavity, it may help to improve the endometrial lining’s thickness, vascularization, and overall quality. This enhanced environment can potentially reduce the risk of complications, such as miscarriage.

PRF therapy holds a significant promise as an autologous approach to enhance the ovarian reserve as well as uterine health to improve reproductive outcomes for women facing fertility challenges.”


“It is difficult to write reviews for fertility clinics since there is so much inherent bias in terms of whether or not one receives a positive outcome. My wife and I, both physicians, understand that online reviews are largely skewed in this regard and tend to focus on things like "customer service" and factors that are somewhat irrelevant to the quality of the medical care received. In our case, however, there is no choice but to give Dr. Acacio and his staff 5 stars.”

“If you want to be treated exceptionally well by helpful staff, a welcoming front office and a highly knowledgeable, caring and responsive clinical team, then look no further. Dr. Brian Acacio and his team helped us conceive and also made sure that we never felt alone in the process. It's an extremely dedicated group of people that genuinely help people fulfill their dream of parenthood.”

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